Modern intravenous fluid therapy in critical care
Extract:
“Intravenous (IV) fluid administration is perhaps the most ubiquitous intervention in perianesthesia and critical care, yet it remains a topic of intense clinical debate. Historically, fluids were viewed as inert volume expanders, often managed with significantly less scrutiny than vasoactive medication or antibiotics. However, current evidence now characterizes IV fluids as complex pharmacological agents with distinct indications, contraindications, and significant potential for harm. Despite common use of IV fluids, surveys of international clinicians reveal a concerning gap in knowledge regarding the specific electrolyte (sodium and chloride) content of different solutions, as well as the physiological consequences of fluid overload.”
Reference:
Pal AD. Navigating Modern Intravenous Fluid Therapy in Critical Care. J Perianesth Nurs. 2026 Jun 19:S1089-9472(26)00191-7. doi: 10.1016/j.jopan.2026.05.039. Epub ahead of print. PMID: 42319319.