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Central venous catheter malposition correction

“Malposition of central venous catheter is a notable technical complication and often need retrieval to avoid further complications. We present a retrospective assessment of case series and literature review of the safety and efficacy of open and endovascular procedures performed to retrieve malpositioned central venous catheters in the subclavian artery” Shehata et al (2025).

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Antimicrobial-induced neutropenia in OPAT

“Data regarding the incidence, onset, and management of complex outpatient antimicrobial therapy-induced neutropenia (COIN) are limited, and pharmacist involvement in COIN management has not been reported” Edwards et al (2025).

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Preventing biofilm formation on central venous catheters – Full Text

“The aim of this study was to evaluate the activity of a cationic arginine-based gemini surfactant, C9(LA)2, against mixed biofilms of fluconazole-resistant Candida albicans and extended-spectrum beta-lactamase (ESBL)-producing E. coli, and the preventive effect of this surfactant impregnated in CVCs on the formation of inter-kingdom biofilms” Pérez et al (2025).

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Impact of OPAT on hospital admission avoidance

“This review underscores the potential for OPAT to optimise hospital resources, improve patient outcomes and lower healthcare costs, advocating for its expansion across NHS trusts to address growing demands for sustainable and efficient healthcare delivery” Acuram et al (2025).

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Prehospital sepsis recognition and antibiotic administration

“For patients in whom a sepsis alert was initiated, EMS clinicians adhered to the sepsis protocol and administered antibiotics prior to hospital arrival in 97% of cases. Patients received their first antibiotic a median of approximately 26 minutes after 9-1-1 call and 11 minutes prior to hospital arrival” Antevy et al (2025).

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Vascular Access and IV Therapy Resource

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Vascular access team review

“Nurse-driven central line insertion (NDCLI) programs offer a proactive approach to address these challenges by empowering trained vascular access nurses to perform CVC and AC insertions” Girgenti et al (2025).

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Impact of OPAT on hospital admission avoidance

“This review underscores the potential for OPAT to optimise hospital resources, improve patient outcomes and lower healthcare costs, advocating for its expansion across NHS trusts to address growing demands for sustainable and efficient healthcare delivery” Acuram et al (2025).

Read More »

Prehospital sepsis recognition and antibiotic administration

“For patients in whom a sepsis alert was initiated, EMS clinicians adhered to the sepsis protocol and administered antibiotics prior to hospital arrival in 97% of cases. Patients received their first antibiotic a median of approximately 26 minutes after 9-1-1 call and 11 minutes prior to hospital arrival” Antevy et al (2025).

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CLABSI in critical care – Full Text

“This study highlights the importance of minimizing CVC use and limiting the number of insertions to reduce CLABSI risk. Effective management strategies should focus on reducing CVC duration and frequency” Alomari et al (2025).

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Blood sampling pain in preterm infants – Full Text

“Based on the results of this study, the use of combined non-pharmacological interventions of NSS has been more effective in reducing the pain caused by venous blood sampling than other conditions where two or one non-pharmacological intervention were used” Yadollahzadeh et al (2025).

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Complications of micropuncture vascular access in the ICU

“Micropuncture vascular access is increasingly being used in the intensive care unit (ICU) due to its perceived reduction of bleeding complications in common ICU procedures. The authors report two rare complications associated with micropuncture kit use associated with vascular access” Okamoto et al (2025).

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Overview of peripheral vasopressor usage

“Peripheral vasopressors were commonly and safely used in our 10-hospital health system, particularly in the community hospitals. Peripheral initiation of vasopressors was not associated with increased mortality at 90 days, but was associated with decreased hospital length of stay” Shyu et al (2025).

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Reducing CLABSI rates in adult ICU

“Central Line-Associated Bloodstream Infection (CLABSI) remains a leading cause of death among critically ill patients. Implementing preventive measures and adhering to best practices is a crucial action to proactively prevent its occurrence” Mhawish et al (2025).

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PICC-related complications

“This study aimed to analyze the influence factors affecting catheter-related bloodstream infection, catheter-related thrombosis and catheter-related local complication, respectively, and to explore the relationship among them, as well as the influence of catheter-related bloodstream infection, catheter-related thrombosis and catheter-related local complication on cancer patients’ death” Weng et al (2025).

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Intravenous fluid contamination study – Full Text

“We reviewed culture-confirmed healthcare-associated outbreaks linked to bacterial and fungal contamination of intravenous fluids and medicines (further “infusates”) in low-income countries and lower and upper middle-income countries (LIC, Lower-MIC and Upper-MIC). We assessed the scope, impact, risks, and gaps in knowledge” Nyandwaro et al (2025).

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Extravasation treatment in a dog – Full Text

“To the authors’ knowledge at the time of submission, this case report documented the first reported clinical use of subcutaneous phentolamine infusion for the management of norepinephrine extravasation in a veterinary species” Flynn et al (2025).

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PICC tip migration in neonates – Full Text

“Peripherally Inserted Central Catheter (PICC) tip migration often occurs after placement despite efforts to position the tip centrally. This study aimed to quantify PICC tip migration within 3-7 h post-insertion and evaluate the effectiveness of manual adjustments for repositioning” Diewo et al (2025).

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