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How to reduce inappropriate use of peripheral IV catheters – Full Text

“The use of peripheral intravenous catheters (PIVCs) contributes to healthcare-associated infections. In 2017, we implemented a multifaceted de-implementation strategy that successfully reduced the inappropriate use of catheters in seven hospitals in the Netherlands (RICAT-1 study). Five years later, we investigated the sustainability of this strategy and the contributing factors” van Horrik et al (2024).

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PICC UEDVT in hospitalised surgical patients – Full Text

“Our study indicates that surgical inpatients are at greater risk of developing PICC-associated upper limb deep vein thrombosis (ULDVT) compared to medical inpatients, with limited evidence supporting the effectiveness of pharmacological thromboprophylaxis in reducing this risk” Li et al (2024).

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Home total parenteral nutrition – Full Text

“This is the first study to present a comparison between home and hospital start TPN in advanced cancer patients, demonstrating that the initiation of outpatient TPN in the home setting is as safe and efficacious as TPN initiated in the hospital” Zhang et al (2024).

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Nursing interventions to prevent PICC complications – Full Text

“This review identified nursing interventions in adults to prevent PICC-related complications, categorized into five main groups: pre-procedure, during the procedure, post-procedure, maintenance, and team management interventions. Nurses are pivotal in averting PICC complications by employing evidence-based nursing interventions at each process stage” Vilão et al (2024).

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Risk factors for extravasation in children

“Extravasation injuries are prevalent in pediatric hospitals and often result in tissue damage and extended hospital stays. However, limited data exist regarding risk factors for extravasation in children. This study aimed to identify these risk factors in pediatric patients receiving intravenous (IV) therapy” Amini et al (2025).

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Heparin versus saline IV flush comparative study

“This nurse-led research study investigates the comparative effectiveness of heparin versus 0.9% sodium chloride locking in blood cancer patients with peripherally inserted central catheters (PICCs). Subjects were randomly assigned to receive either heparin or 0.9% sodium chloride locking for up to 7 days” Denke et al (2025).

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Untoward impact of misdiagnosed penicillin allergy – Full Text

“This review seeks to present the clinical phenotypes with which a beta-lactam allergy may present, define the untoward effects that a fictitious penicillin allergy label may confer to a patient, and propose clinical investigational prompts for nurses and other allied health professionals when interacting with a patient that has a penicillin or other beta-lactam allergy in their medical history” Johannesmeyer (2025).

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Infusion pump flow accuracy systematic review

“Intravenous pumps (IVPs) deliver IV medications to millions of acute care patients each year and result in many adverse events reported to the US Food and Drug Administration (FDA). Although the use of IVPs has improved overall safety, there are still high rates of error that risk the safety of all patients, especially those of advanced age and those suffering from critical illness” Blake (2025).

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Care and maintenance of peripheral IV cannula – Full Text

“Findings showed that poor peripheral intravenous cannulation practice and care which was predicted by work experience, existence of guidelines, and training. As a result, Nurses and midwifes must keep up to speed with focused in-service training, access, and/or follow thorough protocol guidelines for the management of peripheral intravenous cannulation” Kefale et al (2024).

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Patient-reported OPAT outcome measures – Full Text

“Patients experienced significant improvements in Health-Related Quality of Life (HRQoL) while enrolled in OPAT and the programme yields high patient satisfaction. Hospitals considering new OPAT programmes should include both patient satisfaction and HRQoL impact in their argument repertoire for the introduction of OPAT” Burch et al (2024).

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OPAT antimicrobial stability testing guidance – Full Text

“In conclusion, harmonization of antimicrobial stability testing to form a global OPAT-specific regulatory framework, particularly considering ‘areas of variation’ amongst current guidance, is required. We call for the development of a global OPAT antimicrobial stability testing framework with consensus from accepted antimicrobial stability criteria, expert opinion and pharmacopoeial best practice” Naicker et al (2024).

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Contaminated blood culture case study – Full Text

“This case highlights the risks associated with empiric antibiotic treatment of patients with suspected bacteremia, the implications associated with improper blood culture collection technique leading to false positive results, and the importance of interpreting a laboratory result within the context of the patient’s clinical status rather than relying solely on Systemic Inflammatory Response Syndrome (SIRS) criteria” Ordookhanian et al (2024).

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Occupational exposure to blood and body fluids – Full Text

“Primary care workplaces where occupational exposure to blood and body fluids may occur should have policies and procedures in place to manage such incidents. All healthcare workers should be immunised against hepatitis B and ideally should have documentation of their antibody response to vaccination” Pierce (2024).

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ChatGPT role in understanding radiopharmaceutical extravasation – Full Text

“Based on these results we concluded that ChatGPT may be a reliable resource for patients interested in radiopharmaceutical extravasations. However, these validated and verified ChatGPT responses differed significantly from official positions and public comments regarding radiopharmaceutical extravasations made by the SNMMI and nuclear medicine staff” Alvarez et al (2024).

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Value of time to positivity in blood cultures – Full Text

“Time to positivity (TTP) refers to the duration required for a microbiological culture test to indicate a positive result, marking the onset of detectable bacterial or fungal growth in the sample. Numerous variables, including patient characteristics, infection source, former antimicrobial therapy, blood sample volume, and sample transportation time can influence the value of TTP” Maffezzoli et al (2024).

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Management of residual volumes in intermittent medication infusions

“This review will improve understanding of current practices by examining flushing procedures used in the management of residual volume, identifying instances when residual volume is discarded, documenting effects on dosing, examining the impact on patient outcomes, and examining possible environmental harm from waste disposal of undelivered medication” Rout et al (2024).

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Peripheral intravenous catheter standard of care

“Our aim is to provide concise guidance that will enhance and standardize practices related to PIVC. By consolidating current standards of practice into a comprehensive document, our framework seeks to advance the quality of care and improve patient safety” Thompson et al (2024).

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Reducing blood culture contamination – Full Text

“The study demonstrated a substantial reduction in blood culture contamination rates through targeted interventions, highlighting the efficacy of combining evidence-based strategies with interdisciplinary teamwork to improve patient care outcomes” Eisenberg et al (2024).

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