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"Because people getting venipunctures in medical and surgical settings usually feel pain and anxiety, the goal of this study was to look at and compare how cryotherapy (CT) and music therapy (MT) affected the levels of pain and anxiety (P&Amp;A) these people felt" Jafarimanesh et al (2025).
Pain and anxiety in vascular access procedures

Abstract:

Purpose: The fear of vascular access procedures reduces patient cooperation, often resulting in unsuccessful venipuncture attempts and prolonging the overall treatment process. Because people getting venipunctures in medical and surgical settings usually feel pain and anxiety, the goal of this study was to look at and compare how cryotherapy (CT) and music therapy (MT) affected the levels of pain and anxiety (P&A) these people felt.

Method: This research utilized a randomized controlled trial methodology. The target population consisted of patients hospitalized in the medical-surgical wards of Valiasr Hospital, Arak, Iran. One hundred twenty patients were purposively selected and then randomly assigned (using block randomization) to one of four groups: MT, CT, combination therapy (COBT), or control. P&A levels were assessed using the Visual Analogue Scale (VAS) and the Visual Anxiety Intensity Scale (VAIS). Data were analyzed utilizing version 21 of the Statistical Package for the Social Sciences (SPSS) software. Descriptive statistics, including mean, standard deviation, frequency, and percentage, along with inferential statistics, such as the analysis of variance test, paired t-test, and Chi-square, were employed for analysis.

Findings: The findings revealed a statistically significant disparity in pain levels among the four groups (P<0.001). The mean pain score in the COBT group (1.66±1.66) was lower than that of the MT group (2.03±1.84) and the CT group (2.43±2.16). However, the three intervention groups (MT, CT, and COBT) showed no notable difference from a statistical perspective (P>0.05). Additionally, a statistically substantial distinction in anxiety levels was observed among the four groups after the study (P<0.05). Both the COBT and MT therapies markedly diminished anxiety severity in comparison to the control group.

Conclusion: The study results demonstrated that MT, CT, and COBT are effective in alleviating P&A in patients having venipuncture procedures. These interventions may serve as valuable complementary or alternative approaches in clinical practice.

Reference:

Jafarimanesh H, Samiei S, Zakerimoghadam M, Zareie M, Suuk AN. The Comparative Effects of Cryotherapy and Music Therapy on Pain and Anxiety in Vascular Access Procedures: A Randomized Clinical Tria. Curr Health Sci J. 2024 Oct-Dec;50(4):488-497. doi: 10.12865/CHSJ.50.04.03. Epub 2024 Dec 31. PMID: 40144941; PMCID: PMC11936077.

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