Central venous access and increased risk for thromboembolism
To investigate if patients receiving neoadjuvant chemotherapy (NAC) for muscle-invasive bladder cancer (MIBC) had an increased risk of thromboembolic events (TEE) and to evaluate when these events occur on a timeline starting from 6 months pre-cystectomy, during NAC-administration and 60 months post-cystectomy” Ottosson et al (2019). Abstract: PURPOSE: To investigate if patients receiving neoadjuvant chemotherapy […]
Blood culture results before and after antimicrobial administration
Administering antimicrobial agents before obtaining blood cultures could potentially decrease time to treatment and improve outcomes, but it is unclear how this strategy affects diagnostic sensitivity” Cheng et al (2019). Abstract: Background: Administering antimicrobial agents before obtaining blood cultures could potentially decrease time to treatment and improve outcomes, but it is unclear how this strategy […]
Extravasated Peripherally Inserted Central Catheter
Intraoperatively, an un-anticipated diagnosis of extravasated peripherally inserted central venous cannula (PICC) was made. Total parenteral nutrition had extravasated into the mediastinum and thorax” Licina (2019). Abstract: A 48-year-old woman was scheduled for flexible bronchoscopy, video-assisted thoracoscopic surgery and mediastinal washout. She had developed voice changes, difficulty swallowing, shortness of breath with a fever and […]
Dosage regimens for meropenem in children with pseudomonas infections
There have been literature reports that some recommended meropenem dosage regimens may fail to meet therapeutic targets in some high-risk children and adults” Hassan et al (2019). Abstract: There have been literature reports that some recommended meropenem dosage regimens may fail to meet therapeutic targets in some high-risk children and adults. We evaluated this observation […]
Security framework for networked infusion pumps
To cover these gaps, this research proposes Integrated Safety, Security, and Privacy (ISSP) Risk Assessment Framework to determine the risk level of the device and required security controls. It is, then applied to a case scenario of an infusion pump and further evaluated by comparing it with current standards and practices” Yasqoob et al (2019). […]
PICC insertion and changes of thrombomodulin and plasma protein C
This study aimed to evaluate the changes and clinical significance of thrombomodulin (TM) and plasma protein C (PC) in patients with cancer before and after peripherally inserted central catheter placement (PICC)” Yan et al (2019). Abstract: OBJECTIVE: This study aimed to evaluate the changes and clinical significance of thrombomodulin (TM) and plasma protein C (PC) […]
Evaluation of incompatible intravenous infusion administration
We aimed to evaluate and quantify incompatible coadministrations of continuous intravenous medication in the daily clinical practice of a PICU/NICU” Häni et al (2019). Abstract: OBJECTIVES: We aimed to evaluate and quantify incompatible coadministrations of continuous intravenous medication in the daily clinical practice of a PICU/NICU. METHODS: We conducted a retrospective, observational study in the […]
Survey of propofol infusions in PICUs in North America
The objective of this survey was to assess the current use of continuous infusion propofol in PICUs across the United States and Canada” Kurek et al (2019). Abstract: OBJECTIVE: The objective of this survey was to assess the current use of continuous infusion propofol in PICUs across the United States and Canada. METHODS: A list […]
CLABSI in children on home parenteral nutrition
Reliable venous access is prerequisite for patients receiving long-term parenteral nutrition (PN)” Trivić et al (2019). Abstract: Reliable venous access is prerequisite for patients receiving long-term parenteral nutrition (PN). However, central venous catheters (CVCs) are an important risk factor for the development of potentially lethal complications, including catheter related bloodstream infection (CRBSI). We have retrospectively […]
CLABSI and central venous catheter management
Despite pathogen-specific guideline recommendations for CVC removal, compliance with national guidelines was poor. CVC salvage was attempted in the majority of CLABSI episodes in our cohort and resulted in a significantly higher treatment failure rate” Hecht et al (2019). Abstract: BACKGROUND: National guidelines recommend removal of central venous catheters (CVCs) for central line-associated bloodstream infections […]
PICC in haematopoietic stem cell transplantation
To analyze the incidence of complications related to the central peripheral insertion catheter and the viability of the infusion of haematopoietic stem cells through volumetric perfusion pumps” Santacatalina-Roig et al (2019). Abstract: AIMS: To analyze the incidence of complications related to the central peripheral insertion catheter and the viability of the infusion of haematopoietic stem […]
History of blood culture technique
In the clinical microbiology laboratory blood cultures are a vital technology for isolating bacteria and fungi” Allerberger et al (2019). Abstract: In the clinical microbiology laboratory blood cultures are a vital technology for isolating bacteria and fungi. They are the reference standard for diagnosing bloodstream infection and are considered a prerequisite for targeted antibiotic treatment […]
Use of intraosseous needles in neonates
IO access should be available on neonatal units and considered for early use in neonates where other access routes have failed” Scrivens et al(2019). Abstract: BACKGROUND: The use of intraosseous (IO) access during resuscitation is widely accepted and promoted in paediatric medicine but features less prominently in neonatal training. Whilst umbilical venous catheterization (UVC) is […]
Unexpected complication of arteriovenous fistula
Incidence of inadvertent arterial puncture secondary to central venous catheter insertion is not common with an arterial puncture rate of
Central line associated blood stream infections in gastroschisis patients
The aim of this study was to determine the risk of central line associated blood-stream infections (CLABSI) in neonatal gastroschisis patients, risk factors, outcomes, and financial implications” Snyder and Burjonrappa (2019). Abstract: PURPOSE: The aim of this study was to determine the risk of central line associated blood-stream infections (CLABSI) in neonatal gastroschisis patients, risk […]
Compartment syndrome of the leg following IO needle Insertion
Intraosseous (IO) needles are used in patients who are critically ill when it is not possible to obtain venous access” Kibrik et al (2019). Abstract: Intraosseous (IO) needles are used in patients who are critically ill when it is not possible to obtain venous access. While IO allows for immediate access, IO infusions are associated […]
Inadvertent arterial placement of central venous catheter
During such an emergency and placing without imaging guidance, sometimes inadvertent placement of CVC in subclavian artery (SCA) can occur” Shaw et al (2019). Abstract: The frequency of placing a central venous catheter (CVC) has increased and it is often performed in emergency situation for venous access. During such an emergency and placing without imaging […]
Safety of peripheral administration of vasopressor medications
Reports of the administration of vasopressors via PiVCs, when given for a limited duration, under close observation, suggest that extravasation is uncommon and is unlikely to lead to major complications” Tian et al (2019). Abstract: OBJECTIVE: Vasopressor medications have traditionally been administered via central venous catheters (CVCs), primarily due to concerns of peripheral extravasation of […]
Novel treatment of a vaccinia virus infection from an occupational needlestick
CDC was notified about an unvaccinated laboratory worker with a needlestick exposure to VACV, who developed a lesion on her left index finger” Whitehouse et al (2019). Abstract: Vaccinia virus (VACV) is an orthopoxvirus used in smallpox vaccines, as a vector for novel cancer treatments, and for experimental vaccine research (1). The Advisory Committee on […]
PICC-PORT totally implantable vascular access device in breast cancer patients
The peripherally inserted central catheter-PORT is a safe vascular device for chemotherapy delivery that achieves similar clinical results as traditional long-term vascular access devices (peripherally inserted central catheter and arm totally implantable vascular access device” Bertoglio et al (2019). Abstract: BACKGROUND AND OBJECTIVES: The increasing use of arm totally implantable vascular access devices for breast […]
Complication of right internal jugular vein catheter insertion
Iatrogenic superior vena cava pericardial fistula caused by central venous catheterization is rare but can lead to life-threatening condition” Bosemani and Sakthivel (2019). Abstract: Iatrogenic superior vena cava pericardial fistula caused by central venous catheterization is rare but can lead to life-threatening condition. Despite the potential risk of pericardial effusion causing pericardial tamponade, a conservative […]
Asymptomatic pulmonary artery embolization port catheter fragment
Broken catheter embolism is a rare but often fatal complication of implantable venous access devices” Tandon et al (2019). Abstract: Broken catheter embolism is a rare but often fatal complication of implantable venous access devices. Prompt removal is key to avoiding an adverse outcome. You may also be interested in… [rp4wp] Reference: Tandon, S., Livingston, […]
Outcome of underfilling of vacuum blood collection tubes
Underfilling of tubes leads to a higher proportion of blood aspirated with high velocity and relevant elevations in LD. This finding should be considered in cases of clinically implausible elevated LD activities” Neuwinger et al (2019). Abstract: Background: Lactate dehydrogenase (LD) activity is routinely monitored for therapeutic risk stratification of malignant diseases, but is also […]
Complications of indwelling port-catheter system for hepatic infusion
We discuss various cases with complications arising in the indwelling port area in hepatic arterial infusion of chemotherapy and report whether the system was salvaged” Ueda et al (2019). Abstract: INTRODUCTION: Regional hepatic arterial infusion of chemotherapy is performed for unresectable liver tumors via percutaneously implanted port-catheter systems; while these port-catheter systems are effective administration […]
Evaluation of an improved small gauge needle for venipuncture in children
Aims were to compare the performances of two Beckton-Dickinson (BD) Vacutainer® Blood Collection Sets in a pediatric setting: UltraTouch™ Push Button (UT-PBBCS) and Safety-Lok™ (SLBCS)” Padoan et al (2019). Abstract: BACKGROUND: Smaller needles gauge (G) may reduce pain and improve vein access in difficult venous access (DVA). Aims were to compare the performances of two […]
Cost analysis comparison between PICC and ports
We conducted a randomised controlled trial including 399 patients with cancer and performed a health economic evaluation investigating the cost related to PICCs and PORTs” Taxbro et al (2019). Abstract: BACKGROUND: A reliable central venous access device is a cornerstone in the treatment of cancer. Both peripherally inserted central catheters (PICC) and totally implanted chest […]
Thrombotic risk associated with femoral inserted central catheters
Our study aimed to scrutinize the incidence and risk factors of femoral inserted central catheter (FICC)-related thrombosis in patients with superior vena cava syndrome (SVCS) undergoing chemotherapy” Hou et al (2019). Abstract: OBJECTIVE: Our study aimed to scrutinize the incidence and risk factors of femoral inserted central catheter (FICC)-related thrombosis in patients with superior vena […]
Image-guided central line placement in children
The aim of this study was to investigate the utility of postoperative chest radiograph (CXR) after image-guided central venous line (CVL) placement in children” Cunningham et al (2019). Abstract: BACKGROUND: The aim of this study was to investigate the utility of postoperative chest radiograph (CXR) after image-guided central venous line (CVL) placement in children. METHODS: […]
Intraosseous administration of hypertonic saline solution
Intraosseous (IO) access is an alternative method of medication and fluid delivery which is not associated with life-threatening complications and can be inserted faster than CVCs” Lawson et al (2019). Abstract: BACKGROUND: Central venous catheters are often used to administer hypertonic saline (HTS) but might be associated with serious complications. Intraosseous (IO) access is an […]
Effect of tunneled peripherally inserted central catheter placement
To compare the effect of tunneled and nontunneled peripherally inserted central catheter placement under B-mode ultrasound’ Dei et al (2019). Abstract: PURPOSE: To compare the effect of tunneled and nontunneled peripherally inserted central catheter placement under B-mode ultrasound. METHODS: A single center, randomized, controlled, nonblinded, prospective trial was conducted in Guangzhou, China, between July 2018 […]