Remifentanil for procedural sedation during central venous catheter insertion
We compared target controlled infusion of remifentanil and local lidocaine infiltration to placebo and local lidocaine infiltration to decrease pain scores during central venous catheter placement” Vardon Bounes et al (2019). Abstract: OBJECTIVE: Central venous catheter insertion is a common practice for anesthetists, but this invasive procedure generates anxiety and pain in patients that are […]
Development of quality indicators for OPAT care
The aim of this study was to develop quality indicators (QIs) for OPAT care that can be used as metrics for quality assessment and improvement” Berrevoets et al (2019). Abstract: BACKGROUND: The aim of this study was to develop quality indicators (QIs) for OPAT care that can be used as metrics for quality assessment and […]
Infusion pump use for hematopoietic stem cell products
Syringe and intravenous infusion pumps are not commonly used to deliver hematopoietic stem cell products (HPCs) due to a paradigm of thought that suggests that the pressure from the pump might damage the HPCs” Kissoon et al (2019). Abstract: Hematopoietic stem cell transplantation using progenitor cells is a potentially curative treatment option for patients with […]
Clinical risk factors for the development of candidemia in home parenteral nutrition
The aim of this study was to investigate the relevance of the reported SNPs in patients receiving HPN, and to explore clinical risk factors associated with candidemia” Wouters et al (2019). Abstract: BACKGROUND: Patients receiving home parenteral nutrition (HPN) have an increased risk for central line-associated bloodstream infections (CLABSIs), including candidemia. Recently, 7 single-nucleotide polymorphisms […]
IV maintenance fluid tonicity and composition influence plasma electrolyte balance
We examined post-surgical hyponatremia, hypokalemia and acute kidney injury (AKI), associated with use of either IMF” Winata et al (2019). Abstract: BACKGROUND: Intravenous maintenance fluid (IMF) tonicity and composition influence plasma electrolyte balance. OBJECTIVE: To determine if hypotonic IMF therapy contributes to post-surgical hyponatremia. SETTING: Single-center tertiary institution. PARTICIPANTS: Adults who underwent major surgery and […]
Assessing sagittal rotation on posteroanterior chest radiographs
The routine application of the distance between the medial end of the clavicles and a line drawn through the spinous processes at the level of the clavicles as a method of assessing degree of sagittal rotation, diagnostic image quality, and need for repeat is flawed” Hardy et al (2015). Abstract: BACKGROUND: Chest radiography is one […]
Dalbavancin use in vulnerable patients receiving OPAT
Importantly, dalbavancin’s real benefits may be in treating complicated infections in vulnerable patient populations, such as persons who inject drugs” Bork et al (2019). Abstract: INTRODUCTION: Dalbavancin is approved for acute bacterial skin and skin structure infections (ABSSSIs) but offers a potential treatment option for complicated invasive gram-positive infections. Importantly, dalbavancin’s real benefits may be […]
Role of the aortic valve in defining the superior vena cava-right atrium junction
The aortic valve (AV) has been used as a surrogate marker for the superior vena cava-right atrium (SVC-RA) junction during the placement of central venous catheters” Hinton et al (2019). Abstract: INTRODUCTION: The aortic valve (AV) has been used as a surrogate marker for the superior vena cava-right atrium (SVC-RA) junction during the placement of […]
Outcomes of extended infusion of peripheral parental nutrition containing amino acids
In some Japanese hospitals, patients using infusion bags for parenteral nutrition containing amino acids have developed Bacillus cereus bloodstream infections” Shiota et al (2019). Abstract: In some Japanese hospitals, patients using infusion bags for parenteral nutrition containing amino acids have developed Bacillus cereus bloodstream infections. We considered that proliferation of contaminated B cereus in the […]
Improving efficiency of financial authorization by establishing a standard infusion workflow
UC Health, an academic health system, is focused on improving the management of infusion therapies for its patients” Boesken et al (2019). Extract: UC Health, an academic health system, is focused on improving the management of infusion therapies for its patients. Upon learning of a new diagnosis, patients can feel scared, confused, and overwhelmed. They […]
Hazard analysis of class I recalls related to infusion pumps
This study aimed to establish a hazard classification framework of medical devices and to apply it over practical adverse event data on infusion pumps” Gao et al (2019). Abstract: BACKGROUND: The adverse event report of medical devices is one of the postmarket surveillance tools used by regulators to monitor device performance, detect potential device-related safety […]
Prothrombin complex concentrate administration via intraosseous access
In patients lacking IV access, effective PCC administration becomes problematic. No previous case reports have documented PCC infusion via intraosseous (IO) or alternative routes in this setting” Peyko et al 92019). Abstract: BACKGROUND: Vitamin K antagonist (VKA) reversal in patients with acute major bleeding and coagulopathy is an example of an urgent intervention in the […]
Embolized guidewire into central aorta following central venous catheterization
During an attempt to insert a central line into the right subclavian vein at bedside, the guidewire inadvertently entered the subclavian artery and embolized distally” Nath et al (2019). Abstract: A 4-month-old preterm, critically ill infant weighing 3.8 kg was admitted to our pediatric intensive care unit with congestive cardiac failure due to a large ventricular […]
Patient with bilateral ectopic subclavian vein catheterization
This case suggests that clinical physician should be careful to prevent catheter heterotopia in subclavian vein catheterization, and postoperative routine chest X-ray examination is necessary to identify position of the catheter” Huang et al (2019). Abstract: One female patient aged 18 years, with severe burns and inhalation injury was admitted to our unit on June […]
Staphylococcus aureus colonization in hemodialysis patients
We prospectively followed a cohort of 86 hemodialysis patients from an outpatient dialysis center over 25 months analyzing S. aureus carrier status, S. aureus infection rates and mortality” Scheuch et al (2019). Abstract: BACKGROUND: Dialysis patients are frequently exposed to Staphylococcus aureus due to stays in dialysis centers, hospitals or rest homes. The hemodialysis vascular access […]
Efficacy and safety of a virtual reality distraction for needle pain in children
To assess the efficacy and safety of a virtual reality distraction for needle pain in 2 common hospital settings” Chan et al (2019). Abstract: OBJECTIVE: To assess the efficacy and safety of a virtual reality distraction for needle pain in 2 common hospital settings: the emergency department (ED) and outpatient pathology (ie, outpatient laboratory). The […]
Short central venous catheter tip results in extravasation
We undertook a quality improvement project involving a standardised bundle of care and a peri-operative central venous catheter insertion checklist with the aim of reducing the risk of such an incident re-occurring.” Hade et al (2019). Abstract: Central venous catheter insertion is a routine procedure performed by anaesthetists in the peri-operative setting. Upper body central […]
Distal end of the CVC damaged due to radiofrequency energy
We present a patient who underwent mitral valve replacement (MVR) and a concomitant CM-IV procedure in which the distal end of the CVC was damaged due to RF energy” de Rooij et al (2019). Extract: “About 12% of patients undergoing cardiac surgery and 30% of patients undergoing mitral valve surgery experience atrial fibrillation (AF).1 The […]
Study of pain response in neonates during venipuncture
This study found that topical anesthetic agents were effective in reducing pain during venipuncture” Kaur et al (2019). Abstract: BACKGROUND: Neonates being nonverbal are unable to express their pain leading to underestimation of their pain and hence insufficient pain relief. Neonatal pain is assessed by pain scales based on the behavioural and physiological changes that […]
Pharmacoeconomic evaluation of antibiotic treatment for complicated skin infection
We performed a network meta-analysis (NMA) to compare the efficacy and safety of antibiotics used to treat inpatients with complicated skin and soft structure infections” Zhang et al (2019). Abstract: Background: Infections due to methicillin-resistant Staphylococcus aureus (MRSA) cause serious health risks and significant economic burdens and the preferred drugs are still controversial. Methods: We […]
Candida catheter-related bloodstream infection in patients on home PN
This review clarifies Candida CRBSI rates by species, risk factors, outcomes, and management to improve effectiveness of HPN programs” Phua et al (2019). Abstract: BACKGROUND: Catheter-related bloodstream infections (CRBSIs) are life-threatening complications for home parenteral nutrition (HPN) patients. This review clarifies Candida CRBSI rates by species, risk factors, outcomes, and management to improve effectiveness of […]
Hydrochloric acid prolongs the lifetime of central venous catheters in patients with bacteraemia
This study investigated if the additional use of hydrochloric acid (HCl) as an intraluminal lock solution may prolong the lifetime of the CVC” Ahmad et al (2019). Abstract: INTRODUCTION: Bacteraemia in adult patients undergoing treatment for leukaemia is common and associated with profound morbidity and mortality. Infections related to the use of a central venous […]
Impact of prophylactic use of taurolidine-citrate lock on CLABSI in children
The aim of the study was to evaluate prophylactic use of taurolidine-citrate (T-C) solution on the number of CRIs” Małgorzata et al (2019). Abstract: Central venous access poses a risk of developing CRIs. The aim of the study was to evaluate prophylactic use of taurolidine-citrate (T-C) solution on the number of CRIs. 97 catheters, used […]
Presence of invasive devices and risk of healthcare-associated infections
The present study evaluated the daily risk of healthcare-associated infections and sepsis (HAIS) events in pediatric intensive care unit patients with invasive devices” Bennett et al (2018). Abstract: The present study evaluated the daily risk of healthcare-associated infections and sepsis (HAIS) events in pediatric intensive care unit patients with invasive devices. This was a retrospective […]
Review of paediatricians who diagnose and manage cellulitis
There is a lack of evidence-based guidance for management of cellulitis and use of outpatient parenteral antimicrobial therapy (OPAT) in children” Ibrahim et al (2019). Abstract: There is a lack of evidence-based guidance for management of cellulitis and use of outpatient parenteral antimicrobial therapy (OPAT) in children. The only published guidelines for skin infections are […]
Investigation of complications following implantable port insertion in cancer patients
This retrospective single-institutional review was performed to identify rates of complications from port placement and potential factors associated with these events” Skelton et al (2019). Abstract: Central venous access devices, specifically implantable ports, play an essential role in the care of oncology patients; however, complications are prevalent. This retrospective single-institutional review was performed to identify […]
Clinical characteristics and outcomes of patients receiving OPAT
In our study, OPAT is found to be efficacious in saving hospitalization’s days, with a low rate of readmissions and complications and a high patients’ level of satisfaction. We therefore conclude that OPAT is feasible and safe” Briquet et al (2019). Abstract: BACKGROUND: Outpatient parenteral antibiotic therapy (OPAT) was not used in Belgium before 2013, […]
Analysis of clinical blood use in emergency blood loss patients
To explore the blood transfusion data of emergency hemorrhage patients, so as to provide the basis for improving the quality of emergency blood transfusion and guiding clinic rational blood transfusion” Jiang et al (2019). Abstract: OBJECTIVE: To explore the blood transfusion data of emergency hemorrhage patients, so as to provide the basis for improving the […]
Antibiotic-impregnated central venous catheters in the neonatal intensive care unit
It is often unclear what proportion of an improvement is attributable to each element of these care bundles and, as such, a single intervention such as antibiotic impregnation of CVCs might have too small an effect to be demonstrable” Khatami and Isaacs (2019). Extract: As Gilbert and colleagues point out,5 other infection prevention strategies in […]
Antimicrobial-impregnated central venous catheters for prevention of neonatal bloodstream infection
We found no evidence of benefit or harm associated with miconazole and rifampicin-impregnated PICCs compared with standard PICCs for newborn babies” Gilbert et al (2019). Abstract: BACKGROUND: Bloodstream infection is associated with high mortality and serious morbidity in preterm babies. Evidence from clinical trials shows that antimicrobial-impregnated central venous catheters (CVCs) reduce catheter-related bloodstream infection […]