Central venous catheter salvage with antifungal lock therapy
Abstract:
We report a retrospective review of pediatric candidal central line-associated bloodstream infections (N = 145) with antifungal lock therapy-based catheter salvage. Rates of recurrence (6%) and mortality (5%) were low at 28 days. At 1 year, earlier catheter removal was associated with lower recurrence rates (21% vs. 45%, P = 0.005), but no significant difference in mortality (13% vs. 5%).
Reference:Walker LW, Nowalk AJ. Clinical and Microbiologic Outcomes of Antifungal Lock-based Catheter Salvage in Pediatric Candidal CLABSI. Pediatr Infect Dis J. 2025 Apr 3. doi: 10.1097/INF.0000000000004820. Epub ahead of print. PMID: 40208923.