In a retrospective study conducted over 12 months in a multi-hospital system, the incidence of bloodstream infections associated with midline catheters was not significantly lower than that associated with central venous catheters” Hogle et al (2019).

Abstract:

In a retrospective study conducted over 12 months in a multi-hospital system, the incidence of bloodstream infections associated with midline catheters was not significantly lower than that associated with central venous catheters (0.88 vs 1.10 infections per 1,000 catheter-days). Additional research is needed to further characterize the infectious risks of midline catheters and to determine optimal strategies to minimize these risks.

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Reference:

Hogle, N.J., Balzer, K.M., Ross, B.G., Wuerz, L., Greendyke, W.G., Furuya, E.Y., Simon, M.S. and Calfee, D.P. (2019) A comparison of the incidence of midline catheter-associated bloodstream infections to that of central line-associated bloodstream infections in 5 acute care hospitals. American Journal of infection Control. December 5th. doi: 10.1016/j.ajic.2019.11.004. [Epub ahead of print].