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"Infusion port catheter malposition, where the catheter tip is located in vessels other than the superior vena cava, is a rare complication of port implantation. This can lead to infusion difficulties or port-related thrombosis” Guo et al (2025).
Repositioning of malpositioned infusion port catheter

Abstract:

Rationale: A totally implantable venous access port is a subcutaneously implantable, long-term infusion device first reported by Niederhuber in 1982.

Patient concerns: totally implantable venous access port provides a reliable venous access route for patients requiring long-term infusion therapy and chemotherapy.

Diagnoses: Due to its advantages of fewer complications, low infection rates, and ease of long-term use, it has become the primary choice for central venous access in breast cancer chemotherapy patients.

Interventions: In 2021, both the American Society of Vascular Access and the European Society for Medical Oncology recommended the optimal position for the catheter tip to beat the cavoatrial junction, where the superior vena cava meets the right atrium. Similarly, domestic guidelines also recommend the cavoatrial junction as the ideal position for the catheter tip.

Outcomes: Infusion port catheter malposition, where the catheter tip is located in vessels other than the superior vena cava, is a rare complication of port implantation. This can lead to infusion difficulties or port-related thrombosis.

Lessons: Therefore, timely intraoperative identification of catheter malposition and effective adjustment is of significant clinical value.

Reference:

Guo L, Li Z, Luo B, Bai Y. Early identification and rapid repositioning of a malpositioned infusion port catheter under real-time ultrasound guidance: A case report. Medicine (Baltimore). 2025 Apr 18;104(16):e42126. doi: 10.1097/MD.0000000000042126. PMID: 40258737.

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