Fluid balance in severe acute ischaemic stroke – Full Text

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“Fluid therapy is commonly used for patients with severe stroke, for whom fluid balance is a safety endpoint for evaluating the therapy. We aimed to investigate the association of fluid balance with 3-month outcomes in patients with severe ischaemic stroke” Liu et al (2025).

Fluid balance after cardiac arrest – Full Text

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“However, the impact of fluid balance has not been analyzed in this setting. This study aimed to assess the impact of fluid balance on mortality during post-CA shock” Didier et al (2025).

OPAT practice guidelines in Germany – Full Text

IVTEAM opat

“OPAT is a safe, cost-effective alternative to inpatient care, requiring specialists’ ID expertise and AMS. The guideline provides a framework for successful implementation in Germany” Tometten et al (2025).

Perioperative fluid therapy narrative review – Full Text

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“fluid administration is an important part of the management of the surgical patient. Fluid can be used to compensate for the normal turnover of fluid and electrolytes (maintenance), to replace losses, to expand the extracellular fluid space to maintain adequate circulation (resuscitation), and to provide nutrition” Lorente et al (2025).

PICC tip malposition in neonates

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“Catheter direction, lesion location and venous placement are independent risk factors for PICC tip malposition in newborns, and some newborns may spontaneously correct within 24 hours” Chen et al (2025).

Sudden thrombus formation detected during central venous catheter insertion – Full Text

central line

“We hypothesize that thrombus formation in this case resulted from a combination of factors. First, ultrasound video revealed extravascular tissue being pulled into the vessel during dilator insertion, potentially exposing circulating blood to tissue factor (the image at 32 s and diagram in the supplement video). Second, the patient’s severely reduced EF may have caused venous stasis” Uchiyama and Tsubokawa (2025).

Ralstonia pickettii bloodstream infection in 2 critically ill patients

clabsi

“The author reports 2 cases of CLABSI with R. pickettii, in pediatric patients from a tertiary care hospital in Karachi, Pakistan. First case was of a 12-day-old male with Atrial Septal Defect and Patent Ductus Arteriosus, who had a peripherally Inserted central catheter (PICC) placed to facilitate nutrition. Second case was of a 7-year-old male with known B-cell acute lymphoblastic leukemia (B-ALL), with PICC line in place for treatment” Khan et al (2025).

WHO priority pathogens in ICU-associated CLABSI

clabsi

“Striking findings revealed WHO priority pathogens dominated the microbial landscape, constituting 76.47% of CLABSI and 82.14% of CAUTI isolates – with critical priority organisms overwhelmingly predominant (83.34% and 91.3%, respectively)” Anand et al (2025).

Large-volume subcutaneous infusions at home – Full Text

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“Emerging themes included universal preference for SC administration and pain points associated with managing medication/supply orders, storing medications/supplies, troubleshooting device issues, performing burdensome medication preparations, priming tubing/needles, inserting/securing needles, programming devices, adapting to device volume constraints, and loading reservoirs or tubing into delivery devices” Franzese et al (2025).