Optimum flushing volume for power-injectable PICC

iv flush

“We concluded that pulsed flushing with 10 ml normal saline immediately after the contrast agent injection was sufficient. Higher flushing volumes did not lead to a better flushing effect; rather, they would only bring unnecessary fluid burden and cost to patients.Patient or public contribution:No patient or public contribution” Guo et al (2026).

Central venous access in pediatric hematology-oncology

vascular access

“In our center, we use a systematic, multidisciplinary workflow to anticipate the treatment trajectory, prioritize venous preservation, prevent complications, and support structured salvage strategies when device dysfunction or infection occurs” Crocoli (2026).

Admixture compatibility studies in parenteral formulations

drug aministration

“This review synthesizes the current scientific understanding of physicochemical and material-based incompatibilities in reconstituted formulations, intravenous drug admixtures, and parenteral nutrition, highlighting their implications for safety and efficacy” Eknure et al (2026).

Peripheral IV catheter flow rates

peripheral iv

“This study evaluated flow rates across various catheter connection adjuncts to identify optimal devices for resuscitation efficacy” Ferguson et al (2026).

Umbilical artery catheter placement – Full Text

vascular access

“Umbilical arterial catheterisation is a routine procedure in neonatal intensive care units but is associated with thrombotic and other complications. This study evaluated the safety of an innovative ultralow umbilical artery catheter (UL-UAC) positioning technique in a cohort of 235 neonates” Tomaszkiewicz et al (2026).

Use of midline catheters in a paediatric intensive care unit

midline catheter

“Clinical utilisation of midlines across implementation phases did not increase overall vascular access harm. The decrease in midline catheter device selection post-implementation highlights the need for sustained strategies” Weber et al (2026).

Intravenous adrenaline use in the critical care setting

drug aministration

“This review synthesises contemporary evidence surrounding adrenaline’s physiological and pharmacological profile, highlighting its role in cardiac arrest, perioperative medicine, sepsis, toxidromes, and specific contraindicated states” Bright et al (2026).

Reconstitution of poorly soluble drugs – Full Text

Drug administration

“Optimal selection of the variety of solvents, the volume of the initial solvent, and the oscillation time in preparing poorly soluble antibiotics can improve the quality of the intravenous infusion” Jiang et al (2025).

Complications of port-a-cath systems – Full Text

iv port

“PCSs are generally safe in oncology patients; infections and thrombosis predominate as PCS-related complications, but rarely require removal, and standardized care enables long-term use, improving patient quality of life” Nemeș et al (2026).

Medication errors involving parenteral nutrition – Full Text

IVTEAM parenteral nutrition

“Parenteral nutrition and concentrated electrolytes are associated with medication errors in pediatrics; however, a systems-based understanding of these errors is lacking. We aimed to describe the errors, contributing factors, and proposed defenses related to these medications in pediatrics” Tuomisto et al (2026).

CLABSI rates in patients with chronic intestinal failure – Full Text

CLABSI

“The incidence rate of CLABSI was lower than reported in other studies in upper-middle-income countries. Depression and the presence of intestinal stomas may be associated with a higher risk of CLABSI, possibly through their impact on self-care and stress-inflammation pathways” González-Salazar et al (2026).

Quality improvement study to reduce CLABSI – Full Text

CLABSI

“entral line-associated bloodstream infection (CLABSI) is a major contributor to morbidity and mortality among neonates admitted to the neonatal intensive care unit (NICU). Point-of-care quality improvement (POCQI) methods can reduce the rate of CLABSI by improving compliance with the care bundle” Biswas et al (2026).

CRBSI among critically ill patients with central vascular access devices

clabsi

“CRBSI significantly worsens outcomes and costs in Chinese ICUs. Prioritizing subclavian catheterization, infection prevention bundles, and gram-negative antimicrobial stewardship is essential. Further research is needed to validate these interventions across diverse settings” Li et al (2026).

Review of antecubital fossa peripheral intravenous catheter insertion

peripheral iv

“This study identifies a clear discrepancy between clinical guidelines and actual practice. Many ACF insertions appear to be based on incorrect assumptions rather than confirmed clinical need. The findings highlight the need for more targeted, evidence-based decision-making in EDs” Xu et al (2026).

Bedside removal of a knotted PICC

picc

“Peripherally inserted central catheters (PICCs) rarely develop true knots, but when they do, forceful removal can precipitate catheter fracture and embolization. Bedside strategies that restore internal support before extraction may prevent escalation to invasive retrieval” Ramacciani Isemann et al (2026).

CRBSI in pediatric hemodialysis – Full Text

CLABSI

“The suboptimal adherence to current VA recommendations and wide variability in catheter care practices including the prevention, diagnosis, and management of CRBSI highlight the need for standardized pediatric-specific protocols to enhance catheter longevity and improve patient outcomes” Bakkaloğlu et al (2026).