Vascular access device complications during OPAT – Full Text

"Complications (i.e., bloodstream infections or venous thrombosis) occurred more frequently in patients with midlines (6.4 per 1,000 line-days) than peripherally inserted central catheters (1.1 per 1,000 line-days)" Kim et al (2026).

"Complications (i.e., bloodstream infections or venous thrombosis) occurred more frequently in patients with midlines (6.4 per 1,000 line-days) than peripherally inserted central catheters (1.1 per 1,000 line-days)" Kim et al (2026).

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Vascular access device complications during OPAT

Abstract:

In this single-center, retrospective cohort study of 1169 patients requiring outpatient parenteral antimicrobial therapy, complications (i.e., bloodstream infections or venous thrombosis) occurred more frequently in patients with midlines (6.4 per 1,000 line-days) than peripherally inserted central catheters (1.1 per 1,000 line-days), adjusted hazard ratio 3.60 (95% confidence interval 1.66-7.81).

Reference:

Kim JJ, Ordaz-Nielsen G, Vu JB, Tran KL, Kim HD, Schoeny M, Lin MY. Complications in patients with midlines compared to peripherally inserted central catheters for outpatient parenteral antimicrobial therapy. Infect Control Hosp Epidemiol. 2026 Jul 17:1-3. doi: 10.1017/ice.2026.10512. Epub ahead of print. PMID: 42464627.