To establish a scientifically grounded and feasible intravenous infusion management protocol for patients with Aggressive behavior due to mental disorders.
Methods: Guided by Donabedian’s theory, an initial draft of the management protocol was developed through a comprehensive literature review and semi-structured interviews with clinical experts. From June to July 2024, two rounds of expert consultation were conducted, and revisions were made until the final protocol was established.
Results: The response rate for both rounds of expert questionnaires was 100%, with authority coefficients of 0.915 and 0.92. After the second round, the coefficients of variation for item importance ranged from 0 to 0.115 and from 0 to 0.107, while Kendall’s W coefficients were 0.506 and 0.628, respectively, indicating statistically significant expert consensus (P < 0.05). Ultimately, the final protocol comprised 3 first-level items, 17 second-level items, and 41 third-level items.
Conclusion: The intravenous infusion management protocol developed on the basis of Donabedian’s theory is both rigorous and targeted, providing a foundation for the comprehensive management of intravenous infusion in patients with aggressive behavior.
Reference:Liu L, Sun Y, Hao Y, Zhang W, Gao Y, Wei Y, Wang L, Wang H. Development of a protocol for intravenous infusion management in patients with aggressive behavior due to mental disorders: A Donabedian framework approach. PLoS One. 2026 May 21;21(5):e0326717. doi: 10.1371/journal.pone.0326717. PMID: 42166448; PMCID: PMC13193540.