PICC in hematological malignancy patients – Full Text

"A 72-year-old woman with severe malnutrition on total parenteral nutrition (TPN) through a left upper extremity peripherally inserted central catheter (PICC) line presented to the emergency department (ED) with 4 hours of swelling around her neck and chest after initiating feeds" Maffetone et al (2026).

"A 72-year-old woman with severe malnutrition on total parenteral nutrition (TPN) through a left upper extremity peripherally inserted central catheter (PICC) line presented to the emergency department (ED) with 4 hours of swelling around her neck and chest after initiating feeds" Maffetone et al (2026).

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PICC in hematological malignancy patients

Extract:

“A 72-year-old woman with severe malnutrition on total parenteral nutrition (TPN) through a left upper extremity peripherally inserted central catheter (PICC) line presented to the emergency department (ED) with 4 hours of swelling around her neck and chest after initiating feeds. She reported one episode of fever the day prior. She was hemodynamically stable. Physical examination revealed swelling of the chest and anterior neck with palpable fluctuance, without erythema or crepitus. Laboratory results demonstrated leukocytosis, elevated procalcitonin, and C-reactive protein levels. Blood cultures were obtained. Computed tomography scans of the neck and chest were obtained.”

Reference:

Maffetone N, Alley E, Brocious BE. Neck Swelling After Total Parenteral Nutrition. J Am Coll Emerg Physicians Open. 2026 Feb 26;7(2):100346. doi: 10.1016/j.acepjo.2026.100346. PMID: 41783381; PMCID: PMC12955615.