Device-associated infection prevention measures in intensive care units
Abstract:
Background: Adherence to prevention guidelines for device-associated infections (DAIs) in intensive care units (ICUs) is critical but often suboptimal. This study assessed awareness, adherence, and barriers to implementing preventive measures for ventilator-associated pneumonia (VAP), central line-associated bloodstream infections (CLABSI), and catheter-associated urinary tract infections (CAUTI) in Iranian ICUs.
Methods: In a multi-center, cross-sectional study using census sampling, a structured questionnaire was administered to the head nurse and attending physician in all 20 eligible medical, surgical, and general ICUs in Iranian teaching hospitals. The survey assessed awareness, self-reported adherence to core preventive practices and perceived implementation barriers. Adherence rates were compared by ICU type.
Results: Mean overall adherence was 77.9%; rates were highest for CAUTI (82.0%) and lowest for VAP (73.5%). Surgical ICUs demonstrated significantly higher adherence for CLABSI (p=.008) and CAUTI (p=.015) prevention compared to general ICUs. The most frequently cited barrier was a lack of periodic staff training (reported by 50% for CLABSI).
Conclusions: Adherence to DAI prevention protocols was moderate, with VAP prevention a key challenge. The primary barriers were organizational, including insufficient training and staff shortages, not a lack of guidelines. Improving adherence requires systemic solutions that address institutional infrastructure, provide sustained training, and ensure adequate staffing.
Reference:
Ghavidel-Sardsahra A, Fattahpour M, Seifi A, Afhami S, Montazeri M, Yekaninejad MS. Assessment of Awareness, Adherence, and Barriers to Device-Associated Infection Prevention Measures in Intensive Care Units: A Multi-Center Cross-Sectional Study. Am J Infect Control. 2026 Feb 21:S0196-6553(26)00100-8. doi: 10.1016/j.ajic.2026.02.010. Epub ahead of print. PMID: 41730336.