"Venous thromboembolism (VTE), compromised of deep venous thrombosis (DVT) and pulmonary embolism (PE), is a well-recognized complication of cancer. In fact, the risk of VTE is 9-fold higher in individuals with cancer compared with those without. Furthermore, cancer-associated VTE may result in interruption of cancer therapies, exclusion from clinical trials, and short- and long-term morbidity and mortality" Henkin et al (2026).

Scans required to diagnose PICC-associated venous thrombosis

Extract:

“Venous thromboembolism (VTE), compromised of deep venous thrombosis (DVT) and pulmonary embolism (PE), is a well-recognized complication of cancer. In fact, the risk of VTE is 9-fold higher in individuals with cancer compared with those without. Furthermore, cancer-associated VTE may result in interruption of cancer therapies, exclusion from clinical trials, and short- and long-term morbidity and mortality. In the United States, PE-attributable mortality in individuals with cancer has actually increased over the last decade, despite numerous innovations in risk stratification and management of PE . Although it may seem like a natural strategy to address the hazard of VTE in patients with cancer, prophylactic anticoagulation has not been proven to lower risk of all-cause or VTE-related mortality and may introduce a higher risk of major bleeding. Accordingly, prophylactic anticoagulation is not prescribed routinely for patients with cancer to prevent VTE or improve mortality.”


Reference:

Henkin S, Piazza G. Venous ultrasonography and computed tomography venography in diagnosis of peripherally inserted central venous catheter-associated venous thrombosis: complementary strategies for expecting the unexpected? J Thromb Haemost. 2026 Jan;24(1):58-60. doi: 10.1016/j.jtha.2025.09.019. PMID: 41500751.