"As an alternative, intravenous heparin was initiated at home via a chemotherapy port, using a portable infusion pump. This individualized approach was implemented without any major complications, and it may represent a practical option for patients with CAS who are either intolerant or refractory to conventional therapies" Kameda et al (2025).
Home intravenous heparin therapy

Abstract:

Cancer-associated stroke (CAS) presents significant challenges regarding secondary prevention. A 48-year-old woman with pancreatic cancer experienced two episodes of large-vessel occlusion stroke was treated by mechanical thrombectomy. Subcutaneous heparin was discontinued owing to skin reactions, and recurrence occurred despite the use of a direct oral anticoagulant. As an alternative, intravenous heparin was initiated at home via a chemotherapy port, using a portable infusion pump. This individualized approach was implemented without any major complications, and it may represent a practical option for patients with CAS who are either intolerant or refractory to conventional therapies.

Reference:

Kameda T, Okada S, Suzuki R, Nishihira T, Mori A, Hidaka Y, Kawakami T, Fujimoto S. Home Intravenous Heparin Therapy via a Central Venous Port for Recurrent Cancer-Associated Stroke Requiring Repeat Mechanical Thrombectomy: A Case Report. Intern Med. 2025 Dec 11. doi: 10.2169/internalmedicine.6405-25. Epub ahead of print. PMID: 41371653.