Extract:
“Intraosseous (IO) access has gained traction as a primary vascular access method during resuscitation. Recent prehospital clinical trials, including the PARAMEDIC-3 trial and VICTOR study, demonstrate no significant difference in 30-day survival between IO and intravenous (IV) access in adult out-of-hospital cardiac arrest (OHCA) patients. This evidence has prompted a trend toward prioritizing IO access during OHCA, with some practitioners continuing its use post-return of spontaneous circulation (ROSC) during in-hospital care. However, only one study has evaluated IO access for in-hospital cardiac arrest (IHCA), raising questions about its broad applicability in IHCA scenarios.”
Reference:Xie R, Xiao L. Intraosseous access in resuscitation. Crit Care. 2025 Oct 21;29(1):445. doi: 10.1186/s13054-025-05651-w. PMID: 41121244.