Vasoactive drug extravasation management
Abstract:
Objective: The aim of this study was to map nursing care in the treatment of lesions due to vasoactive drug extravasation. This scoping review is built according to the recommendations of the Joanna Briggs Institute and PRISMA-ScR.
Methods: The review was carried out from July to August 2022, across 12 data sources. The evidence was evaluated using PAGER.
Results: Initially, 2124 studies were found. After screening and complete analysis, 12 were left, which were used for a reverse search in the literature, which resulted in 20 studies, for a total of 32 studies. The main types of care found included interruption of vasoactive drug infusion, drainage of the extravasated solution, removal of the catheter, hot or cold compresses, elevation of the limb, phentolamine, topical nitroglycerin 2%, infusion of hyaluronidase, flush-out or salt washing technique, and autolytic debridement.
Conclusion: The interventions demonstrated repetitions in several studies, low variety in treatment, and low methodological rigor.
Reference:
de Lima CA, Sena BO, Bispo MM, das Chagas ALG, Barros Ribeiro KR, de Oliveira E Araújo R. Nursing Care in the Management of Injuries Due to Vasoactive Drug Extravasation: Scoping Review. J Infus Nurs. 2025 Sep-Oct 01;48(5):318-337. doi: 10.1097/NAN.0000000000000604. Epub 2025 Aug 27. PMID: 40910678.