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"Here, we report the case of a severe episode of anaphylaxis attributed to a chlorhexidine-coated CVC in a middle-aged man who presented for an L5-S1 Anterior Lumbar Interbody Fusion (ALIF) revision due to hardware failure" Ali et al (2025).
Anaphylaxis secondary to central venous catheter placement

Abstract:

Central venous catheters (CVCs) are often used intraoperatively for large volume resuscitation and the administration of vasoactive medications. Many of these catheters are impregnated with antimicrobials to prevent infection but independent reports of anaphylaxis directly following catheter placement have been increasing. Here, we report the case of a severe episode of anaphylaxis attributed to a chlorhexidine-coated CVC in a middle-aged man who presented for an L5-S1 Anterior Lumbar Interbody Fusion (ALIF) revision due to hardware failure.

Reference:

Ali Y, Gonzalez A, Pallan J, Bergbower EAS. A Rare Case of Intraoperative Anaphylaxis Secondary to Central Venous Catheter Placement: A Case Report. Case Rep Anesthesiol. 2025 Feb 11;2025:1310392. doi: 10.1155/cria/1310392. PMID: 39968323; PMCID: PMC11835472.

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