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"A model to simulate CVC colonization and contamination compared standard cultures with ISDD technique. ISDD detected 100% of colonized CVCs while decreasing false-positive cultures from 36% to 16%" Rupp et al (2024).
Assessment of blood culture initial specimen diversion device

Abstract:

The role of initial specimen diversion devices (ISDDs) in preventing contamination of central venous catheter (CVC) blood cultures is undefined. A model to simulate CVC colonization and contamination compared standard cultures with ISDD technique. ISDD detected 100% of colonized CVCs while decreasing false-positive cultures from 36% to 16%.

Reference:

Rupp ME, Fey PD, Lyden E, Handke L. In vitro assessment of effect of initial specimen diversion device on detection of central venous catheter contamination or colonization. Infect Control Hosp Epidemiol. 2024 Dec 19:1-4. doi: 10.1017/ice.2024.220. Epub ahead of print. PMID: 39696936.

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