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Impact of lock solutions on polyurethane central venous catheters

"The impact of ethanol locks on the mechanical performances of central venous catheters was compared to that of aqueous-based locks. Several mechanical tests were performed to evaluate catheter behavior: kinking radius measurements, burst pressure, and tensile tests" Khzam et al (2023).

"The impact of ethanol locks on the mechanical performances of central venous catheters was compared to that of aqueous-based locks. Several mechanical tests were performed to evaluate catheter behavior: kinking radius measurements, burst pressure, and tensile tests" Khzam et al (2023).

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Impact of lock solutions on polyurethane central venous catheters

Abstract:

The impact of ethanol locks on the mechanical performances of central venous catheters was compared to that of aqueous-based locks. Several mechanical tests were performed to evaluate catheter behavior: kinking radius measurements, burst pressure, and tensile tests. Different polyurethanes were studied to assess the impact of radio-opaque charge and polymer chemical composition on catheter behavior. The results were correlated to swelling measurements and calorimetric measurements. In particular, ethanol locks have a higher impact on long contact time than aqueous-based locks: stresses and strains at break were lower, and kinking radii were higher. However, for all catheters, the mechanical performances remain much higher than the normative requirements.


Reference:

Khzam A, Saunier J, Carpentier L, Mignot A, Tortolano L, Yagoubi N. Impact of lock solutions on the mechanical performance of polyurethane central venous catheters: A comparative study. Med Eng Phys. 2023 Jul;117:103994. doi: 10.1016/j.medengphy.2023.103994. Epub 2023 May 17. PMID: 37331749.

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