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"Subcutaneous (SC) administration of medications and fluids is underutilized in the US despite reported benefits. It is easier to access and maintain compared with intravenous (IV) placement" Tang et al (2023).

Subcutaneous vs IV drug and fluid administration

Extract:

“Subcutaneous (SC) administration of medications and fluids is underutilized in the US despite reported benefits. It is easier to access and maintain compared with intravenous (IV) placement. The site may be used for 7 days or more. Patients are free of the burden of IV pumps, allowing for greater mobility. There are also cost-saving benefits. In the US, SC and IV drugs are coded, managed, and billed differently. For example, SC administration of rituximab and infliximab for treatment of rheumatoid arthritis provides an estimated cost savings of $16 000 per patient, and SC infusions given intermittently by gravity eliminate the costs for IV pumps.”


Reference:

Tang M, Abdelaal M, Lau J, Ruiz Buenrostro A, Chen M, Zimmermann C, Bruera E. Subcutaneous vs Intravenous Administration of Medications and Fluids for Patients With Cancer in the US and Canada. JAMA Oncol. 2023 Mar 23. doi: 10.1001/jamaoncol.2023.0239. Epub ahead of print. PMID: 36951869.

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